Paxillin phosphorylation sites mapped by mass spectrometry.
نویسندگان
چکیده
sites mapped by mass spectrometry Donna J. Webb1,*,‡,§, Melanie J. Schroeder2,‡, Cynthia J. Brame4, Leanna Whitmore1, Jeffrey Shabanowitz2, Donald F. Hunt2,3 and A. Rick Horwitz1 1Department of Cell Biology, 2Department of Chemistry, and 3Department of Pathology, University of Virginia, 1300 Jefferson Park Avenue, Charlottesville, VA 22908, USA 4Department of Biology, Centenary College of Louisiana, 2911 Centenary Avenue, Shreveport, LA 71104, USA
منابع مشابه
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متن کاملThe noncatalytic domain of protein-tyrosine phosphatase-PEST targets paxillin for dephosphorylation in vivo.
The noncatalytic domain of protein-tyrosine phosphatase (PTP)-PEST contains a binding site for the focal adhesion-associated protein paxillin. This binding site has been narrowed to a 52-residue sequence that is composed of two nonoverlapping, weak paxillin binding sites. The PTP-PEST binding site on paxillin has been mapped to the two carboxyl-terminal LIM (lin11, isl-1, and mec-3) domains. Tr...
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ورودعنوان ژورنال:
- Journal of cell science
دوره 118 Pt 21 شماره
صفحات -
تاریخ انتشار 2005